#1 Marlon Brando and Johnny Depp were fans of Beavis and Butt-Head and would often do the characters' voices on the set of Don Juan DeMarco.
#2 Doug was initially going to be called Brian, but Jim Jenkins, the shows creator felt it sounded too fancy.
#3 Three teenagers wrote the "Buster and Babs Go Hawaiian" episode on Tiny Toon Adventures.
#4 Rocko from Rocko's Modern Life was initially supposed to be yellow.
#5 Rugrats co-creator, Arlene Klasky asked herself the question, "If babies could talk what would they say?" and that led to the creation of the cartoon.